GDPUK.com - Study provides evidence that BRONJ is a rare occurrence

Study provides evidence that BRONJ is a rare occurrence

Details: Published: Monday, 10 December 2012 07:44; Written by News Editor; Hits: 2049

A two-year national study based on patient case records has concluded that incidence of bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be considered as rare. This study was a collaboration between the Faculty of General Dental Practice (UK) (FGDP (UK)) and the British Association of Oral and Maxillofacial Surgeons (BAOMS).

The study was designed to capture all new referrals of patients with avascular necrosis of the jaw, including BRONJ, to oral and maxillofacial departments and dental hospitals in England, Wales, Scotland and Northern Ireland, from June 2009 to May 2011.

BRONJ can develop as an adverse effect of taking bisphosphonate medication, used for the management of osteoporosis and in the treatment of some cancers. Up until now there have been no published studies providing a reliable estimate of the incidence of avascular necrosis, specifically BRONJ, in the general population; this study aimed to give a better understanding of incidence, case management and risk factors in relation to outcome for patient care management.

Clinical leads for the study were Professor Simon Rogers for BAOMS and Dr Nikolaus Palmer for the FGDP(UK), while other stakeholders included the British Society of Oral Medicine, the British Association of Oral Surgeons and the Faculty of Dental Surgery of the Royal College of Surgeons of England.

Professor Simon Rogers: “Although the data need to be interpreted with caution, the report would suggest that there are around 600 cases of BRONJ each year in the UK, and around 400 of these are related to oral bisphosphonates. Considering how commonly bisphosphonates are prescribed for conditions such as osteoporosis, these results should serve to reassure the public given the relative small number of cases of BRONJ each year. Further data and research is required.”

Bill Inness 11 years 11 months

what percentage of patients taking bisphosphonates who have an extraction develope BRONJ?

Alan Aungier 11 years 11 months

BRONJ

600 cases of BRONJ each year is a "rare" occurance in the context of general population incidence.

However what is the incidence in the patient population that actually take these drugs.

Anyone got access to the full text of the above study

Ray McNamara 2 years 3 months

MRONJ

Please could we use the correct acronym?
I’ve seen it twice but now always place an L-PRF plug and no problem since

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Study provides evidence that BRONJ is a rare occurrence

BRONJ

MRONJ

Report